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ABCD NATIONAL CONGRESS 2019 (Associazione di Biologia Cellulare e del Differenziamento)

The upcoming ABCD Congress will be held in Bologna (Italy) from 19 to 21 September 2019.

This event will bring together scientists from across the world and will offer an invaluable opportunity to discuss scientific issues in the fields of cell biology and differentiation. 

The congress will be open to all researchers from Italy and abroad and will include a full range of academic sessions, plenary lectures, and social/cultural events.  The meeting specially encourages participation from young researchers.

In this edition ABCD has the pleasure to hosting outstanding international scientists, some of them Nobel Prize winners. Their participation will make the meeting a special event in which researchers will have the opportunity to friendly and informally talk with such prestigious scientists thus encouraging and fostering the participation of young scientists at the scientific discussion during the event.

 More information will be available soon through the website https://abcd2019.azuleon.org/welcome.php

 

 

Seminar announcement Marco Sandri, May 30, 2019

Aspetti statistici nella sperimentazione con uso di animali

Dott. Marco Sandri

Consulente statistico OPBA

30 Maggio 2019

ore 11.00-13.00

Aula U 1.2 MO51

Via Campi, 103
 

Scarica la locandina

 

Centre for Regenerative Medicine - 10th Anniversary

"Il Centro di Medicina Rigenerativa “Stefano Ferrari”: 10 anni di successi internazionali"

After ten years of existence, the Centre for Regenerative Medicine "Stefano Ferrari" celebrates its successes.

2019 February 28th , 9 AM

Sala Eventi del Tecnopolo -Via Vivarelli, 2 Modena. 

To dowload the flyer click here.

 

 

 

Seminar announcement Prof. Sampaolesi- February 19, 2019

Single cell OMICS, cell reprogramming and gene editing to challenge muscular dystrophies

Prof. Maurilio Sampaolesi

Stem Cell and Developmental Biology, KU Leuven, Belgium

Human Anatomy Institute, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Italy

Tuesday, February 19th, 2019 
h. 15.00
Room U 1.1 [MO 51] 
Via Campi 103 - Modena

 

Abstract:

Muscular dystrophies (MDs) are inherited diseases caused by progressive degeneration of multinucleated skeletal muscle fibers that constitute the most abundant tissue of the human body. Any cell or gene replacement strategy must restore proper gene expression in hundreds of millions of post-mitotic nuclei embedded in a dense sarcoplasm surrounded by thick sarcolemma. Facing this complex situation, clinical trials for MDs have met with modest success, mainly due to the inefficient delivery of viral vectors or donor cells to dystrophic muscles. The current therapeutic approaches for MDs remain mainly steroids and assisted ventilation that cannot counteract fibrosis and fat replacement in dystrophic muscles. Thus, there is an urgent need to develop the next-generation of viral vectors (1, 2) and stem cell-based protocols (3, 4) for the treatment of MDs. 
We provide evidence that epigenetic mechanisms influence the commitment of isogenic induced pluripotent stem (iPS) and mesodermal iPS cell-derived progenitors (MiPs) toward the striated muscle lineages (3). Subsequently, we conjugated the MiP–based approach with genome editing correction and TALEN-corrected canine dystrophic MiPs resulted in functional striated muscle regeneration. In addition, integrating RNA-seq and miRNA-seq data, we defined miRNA cocktails that promote the myogenic potential of human MiPs (4). However, the observed improvement seen with cell-based therapies still does not have an impact on the diffused fibrosis and fat replacement responsible for the loss of mobility in dystrophic patients. Thus, to further gain insight on the cell heterogeneity in skeletal muscle, we recently used single-cell RNA-sequencing to decomplexify interstitial cell populations in healthy and dystrophic skeletal muscles. We identified a CD142 (F3) positive population in mice and humans that is responsible for the inhibition of adipogenesis. The discovery of these adipo-regulatory cells in skeletal muscles aids our understanding regarding the aberrant fat deposition in MDs, paving the way for therapeutic treatments that potentially sustain ambulation in MD patients.
 
1. Sarcar et al. Nat Commun. 2019 Jan 30;10(1):492.
2. Neyrinck et al. Theranostics. 2018 Apr 14;8(10):2799-2813
3. Quattrocelli et al. J Clin Invest. 2015 Dec;125(12):4463-82
4. Giacomazzi et al. Nat Commun. 2017 Nov 1;8(1) 
 
To download the flyer click here
 

PhD Thesis Defence 2019

Wednesday, February 20, 2019
9:00 AM
Room U0.2 - [MO 51] - Via Campi 103 - Modena

To dowload the program click here

 

Seminar announcement Dr. Greenland- February 22, 2019

The need for cognitive science in statistics

Sander Greenland, DrPH

Emeritus Professor of Epidemiology and Statistics, UCLA School of Public Health,

Los Angeles, California

 

February 22, 2019 - 11:30

Aula CS 0.1 - Centro Servizi Medicina

Largo del Pozzo 71 - Modena

To dowload the flyer click here.

 

Seminar announcement Dr. Laura Zoppi, December 3, 2018

Publishing in Nature Research journals

Laura Zoppi (Nature Research, Springer Nature, Berlin, Germany)

Monday December 3, 2018 - 11.00  
CNR S3 Seminar Room, Third Floor, Physics Building, FIM Department

October 18, 2018

15:00-16:00

Room CS0.2
[MO36] Centro Servizi (Medicina-Policlinico), via del Pozzo 71, Modena

Abstract: 

Publishing your work in an influential journal begins with good research, but there is much more to it. This talk aims to demystify the editorial process at Nature Research journals, including Nature, Nature Chemistry, Nature Materials and Nature Communications. What takes a paper from new submission to accepted article? We will discuss what our editors look for in potential papers — and how best to communicate your work to the editor and reviewers to ensure the point gets across — and walk through all stages of the peer review process, from how editors select referees, to how we make decisions from a set of reports. You will also learn the keys to fashioning a convincing response letter and putting together a successful appeal.

Laura Zoppi is an associate editor at Nature Communications, where she handles content covering computational material science, computational chemistry and machine learning areas.

Host: Massimo Rontani massimo.rontani@nano.cnr.it

 

Seminar announcement Khalid Shah, MS, PhD- October 18, 2018

Receptor Targeted Engineered Stem Cells: Therapeutic Application For Cancer & Beyond

Khalid Shah, MS, PhD
Director, Center for Stem Cell Therapeutics and Imaging
Harvard Medical School, Boston, USA
Director, Center for Excellence in Biomedicine
Vice Chair of Research
Brigham and Women's Hospital, Boston, USA
Principal Faculty
Harvard Stem Cell Institute, Cambridge, USA

October 18, 2018,  15:00-16:00
Room CS0.2
[MO36] Centro Servizi (Medicina-Policlinico), via del Pozzo 71, Modena

 

To download the flyer click here.

 

Seminar announcement, Alexander M.M. Eggermont, July 17, 2018

The Immunotherapy Revolution: Lessons from Melanoma

Alexander M.M. Eggermont, MD, PhD
Directeur Général Gustave Roussy
Professeur Oncologie,
Université Paris-Sud, Paris, FRANCE

 

July 17 2018
12.30-13.30
Toom T01 - CS01

Centro Servizi Facoltà di Medicina
Modena

 

To dowload the flyer click here .

Alexander M.M. Eggermont - Biosketch

 

Seminar announcement Prof. Silvio Bicciato, July 17, 2018

Bioengineering approaches for genomic data analysis
in precision medicine

Prof Silvio Bicciato
Center for Genome Research.
Dipartimento di Scienze della Vita, UNIMORE

July 17 2018
14.00
Room COM- IV floor

Modena

 

To dowload the flyer click here .