Epigenetics in Aging and disease- XL Cycle

1.5 CFU

Schedule: First year, Second year

Programme

The course will focus on the description of general epigenetic mechanisms, diseases in which epigenetics play important mechanistic role (hereditary diseases e.g. Rett-syndrome and acquired diseases e.g. AML), animal models which demonstrate the role of epigenetics, and molecular techniques to investigate epigenetic modifications. Purpose: The participants shall obtain in-depth knowledge of epigenetics as basis of human disease and experimental approaches and model to investigate epigenetic modifications

Intended learning outcomes

At the end of the course the participants will be able to:

• Understand epigenetic modifications and its implications in aging and disease
• Discuss advantages and limits of experimental models and approaches
• Critically assess the concept of epigenetic modifications

Teaching and learning activities

Lectures will be integrated by interactive discussion with students. Participants will be also invited to critically evaluate the possible
contribution of epigenetic modification in their research project.